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If it is covered by your SOPs, follow them. If you suspect that there are abuses via manual integration and there is no SOP covering this, maybe it’s time to
30 Quality Systems Chapter 5, Control of Data Section c) The laboratory shall establish SOPs addressing manual calculations including manual integrations.
In such cases, the baseline correction line can be changed manually by setting peak integration parameters (or peak integration commands) for individual sets of
The proper measurement (integration) of the peak areas in analytical will be controlled by a standard operating procedure (SOP) or similar document,
The process of integrating child peaks on the front (upslope) of a peak subject to specified Audit trails should be reviewed in accordance with an SOP.
This SOP is applicable to all chromatographic data generated at the United States Manual integration will be employed to correct an improper integration
Standard operating procedure for working with HPLC and GC analysis of pharmaceutical 5.8.1.4 The integration parameters must be optimized for the entire1.1 This Standard Operating Procedure provides guidance on the proper way to integrate chromatographic peaks. Integration of peak areas is commonly required to.
Having a set of SOPs for integration is critical to ensuring proper and defendable processing of data. This should not just include manual integration, but also
“Manual Integration” is the process employed by the Manual integration is performed by the ✓EPA Region 9 SOP #835, “Chromatographic Integration.
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